MSMEG1012
ms1012
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1081451 – 1082986
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs MAB0087c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1009 MSMEG1010 MSMEG1011 MSMEG1012 MSMEG1013 dinB MSMEG1015
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1012_MSMEG1012_dna
CCGCACCGCGGCCACCCGGACGCAGGTCGTGGTGGTCACGCACTCGCGTGCGCTGCTGGAGTTCCTCGACACCACCCCGATCGGCGACGATGGTCCGGGTGGCGCCGTCGAGATCGAGTTGTACAAGCAGTGGGGCGAGACCAAGGTGACCGGGCAGGGCCTGCTCTCGACGCCGTCGTGGCACTGGGGAAACCGCTAGGTCCTGAACAGTTCGTGTTCAGGTCAGTGTCCGTTCATCTGCGTCGGCTTATGTGACTCGCGATCAGTTCACACGAATCTCACACGAGTCTAGGAGAAGCCGTGCCTGTCAGTACCTATCTCAGAGCGACGGTGGTGATCGTGGCAGCCGCGCTGCTGCCGCTCACGGCCTGCAGCAGCGACACCACCACGGAGTCCAGCGGTGACACGGTGCACCGCTCGGCCGACGGCGACATCGTGACCAACGGTGGCGCGCGCCGTATCGACGGCGACCAGACCGACACCGAGCGCAGCGCGATCAACGGCGGCAAGGCCCGCAATGTCATCCTGCTGGTCGGCGACGGCATGGGCGACTCGGAGATCACCATGGCCCGCAACTACGAAAAGGGCGCAGGCGGAAGCTTCGACGGCCTCGACGCGCTGCCGCTGAGCGGGCAGTACACCACCTACGCGCTCAACAAGGACGGTAAGCCCAACTACGTCACCGATTCGGCCGCGAGCGCCACGGGATGGACCACCGGCACCAAGACCTACAACGGCGCGCTGGGCATCGACATCAAGGGCAACCCGCAGAAGACGATCCTCGAACTCGCCAAGGCACAGGGTTTCGCGACCGGTGACGTCACCACGTCGGAGATCCAGGACGCCACCTCGGCGTCGCTGTTCTCCCACATCAGCGAGCGTGACTGCTACGGCCCGGTCCAGACCGCAGCCGATTGCGCGGCCGACGCCCTGGAGAACGGCGGGCCGGGTTCGGTGACCGAGCAGTTGCTGACCACCCGCCCGGACCTGACATTGGGCGGCGGCGCCGAGACGTTCTCCCAGACCGCGAACGGCGGCGAGTACAAGGGCAAGACGCTCGAAGCCCAGGCCAAGGAGCGTGGGTTCCAGATCGTGCGCACCGCAAGCGAACTCGACGCCGTCACCGCGGCCGATCAGGACAATCCGGTGATCGGGCTGTTCGCCGACGGCAACATGCCGGTGCGCTGGTCAGGCCCGCCCGCCGTGCGCCACGGCTACCTGCAGCCCGCGGCCAAGTGCACCGACAATCCCGAGCGCGGGTCCGAGGTCCCCAGGCTGGCCGCGATGACGCAGAAGGCCATCGATCTGTTGAAGAACGGAAAAGCCGGTCAGGACAAGGGCTTCTACCTGCAGGTGGAAGGCGCGTCGATCGACAAGAAGGACCACGACGCCGACCCGTGCGGCCAGATCGGCGAGACGGTGGACTTCGACGAGGCCGTGCAGACCGCGCTCAACTTCGCCCGCGAGGACGGCAACACGCTGGTCGTCGTGACCGCCGACCACGGTCACAGCAGCCAGATCGTGGAGGCCCTCAGCGAGGACGACCTGCGCGACATCGCCGAGGACACCAAGCAGCCCGTCGAGCGGGTCCGCGACACCATGTACCCGGGCCTGACCCGCAAGCTCGTCACGGCCGATGACGCCGAGATGACGGTCAGCTACGGCACTTCCGCCGATGTCGACGTCGAGAGCGAGACCCACACCGGAACCCAGGTGCGTGTCGCGGCCTTCGGTCCGAGGGCCGCGAACGTCGTCGGGCTGACCGATCAGACCGATCTGTTCTTCACCATGACCGATGCGCTCGGCCTCGACCGCGGGGAGGAACCCGCGCACTGA

Protein Sequence 

>Ms1012_MSMEG1012_protein
VPVSTYLRATVVIVAAALLPLTACSSDTTTESSGDTVHRSADGDIVTNGGARRIDGDQTDTERSAINGGKARNVILLVGDGMGDSEITMARNYEKGAGGSFDGLDALPLSGQYTTYALNKDGKPNYVTDSAASATGWTTGTKTYNGALGIDIKGNPQKTILELAKAQGFATGDVTTSEIQDATSASLFSHISERDCYGPVQTAADCAADALENGGPGSVTEQLLTTRPDLTLGGGAETFSQTANGGEYKGKTLEAQAKERGFQIVRTASELDAVTAADQDNPVIGLFADGNMPVRWSGPPAVRHGYLQPAAKCTDNPERGSEVPRLAAMTQKAIDLLKNGKAGQDKGFYLQVEGASIDKKDHDADPCGQIGETVDFDEAVQTALNFAREDGNTLVVVTADHGHSSQIVEALSEDDLRDIAEDTKQPVERVRDTMYPGLTRKLVTADDAEMTVSYGTSADVDVESETHTGTQVRVAAFGPRAANVVGLTDQTDLFFTMTDALGLDRGEEPAH

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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