MSMEG1027
ms1027
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1095088 – 1095966
Vulnerability Index (VI):
M. tuberculosis homologs Rv0791c, Rv1855c, Rv2893, Rv0044c, Rv2951c
M. abscessus homologs MAB4496c, MAB4797, MAB0968c, MAB3792, MAB3016c, [+ 7 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1022 MSMEG1023 MSMEG1024 MSMEG1025 MSMEG1026 MSMEG1027 MSMEG1028 MSMEG1029 MSMEG1030
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1027_MSMEG1027_dna
CGCGTGGGGAAGTGCCGGTAGATGGTGCCCATGCCGACGCCGGCGCGGGCCGCGATATCGCGCACCGGCACCTCCACGCCCGCGGCCACGAACGCCGCGGCCGCGGCCTCCAGAAGCGCCTGCTCGTTGCGGCGCGCGTCGGCGCGCTTTCGCGTCGTCTTGTCGGCGTCGGGCATCCGGAGATCCTCTCGTCCCTTGATAAGCGGAACGACGCTCCGTATCGTAGGGGGAGCATTGTTCCGCTTATATGGTGCCAGGCGGGTGCGCCCGTCCGTCGGCATCCGGTGAAAGGCCCGCCCATGTCACTTGCCGAGAATGTGCAGTTCGGCATCTTCACGCCTCCCCATCAGGTCGATTACGCGGATCTGTTGCGCGTCTGGACGGAGGCCGACGAGATCCCCGAGATCGCGCACGCCTGGCTGTTCGACCACCTGATCCCGATCGCGGGAGACGTCACCGGACCTGTGCTCGAGGGGTGGACGCTACTGTCGGCGCTCGCGGCGCAGACGAAGCGTCTGCGTATCGGTTTGATGGTGACCAGCAACAGGTTTCGGCCACCGTCCATGCTCGCCAAGATCGCCACGACCGTCGACATCGTGTCCGGTGGTCGTCTCGATTTCGGCATCGGGTCGGGCTCGCGGCCCGGTCATCCCGTCGCACGGCACGAGTACATCTCGAACGGGCTGCCCTACCACGACGCCGACCACGCGGTCGCGAGTCTGGCCGAGGCGTGCACGCTGATCCGCCGGTTGTGGGCCGAGGAGGAACCGTTTGACTTCGACGGCGGCTTCTACCGATTGGAGCGCGCGTTCGCCAACCCCAAACCGGTGCAGCGGCCCCACCCGCCGATCGTCATCGGCGGACGCGCCAAGGCCACGCTCCGAGTGGTTGCCGAACACGCCGACGTCTGGAACATCCCCGGCGGCGACATCGAGGACATGGTGCGCCGCAGCGAGATGCTCGACAGTTACTGCGCCGAAATCGGCCGGGACCCAAAGGAGATCGCGCGGTCCACGGTGCTCGGAGTGTCCTACGACCAGCCGGGGCAGACCCGGGCCGCGGTGAAAGAAGCCGTCGACGCCGGGTTCGGCCACATCGTCCTGATGCTGCCGACCCCGTACCCCGACAACGTCGTCCGCTGGGGCGTCGACGAAATCGTCACGCCCACGGCGTCATAG

Protein Sequence 

>Ms1027_MSMEG1027_protein
MSLAENVQFGIFTPPHQVDYADLLRVWTEADEIPEIAHAWLFDHLIPIAGDVTGPVLEGWTLLSALAAQTKRLRIGLMVTSNRFRPPSMLAKIATTVDIVSGGRLDFGIGSGSRPGHPVARHEYISNGLPYHDADHAVASLAEACTLIRRLWAEEEPFDFDGGFYRLERAFANPKPVQRPHPPIVIGGRAKATLRVVAEHADVWNIPGGDIEDMVRRSEMLDSYCAEIGRDPKEIARSTVLGVSYDQPGQTRAAVKEAVDAGFGHIVLMLPTPYPDNVVRWGVDEIVTPTAS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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