MSMEG1030
ms1030
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1098227 – 1099726
Vulnerability Index (VI):
M. tuberculosis homologs Rv3049c, Rv1393c, Rv0892, Rv0943c
M. abscessus homologs MAB3920c, MAB2074, MAB2073, MAB4476c, MAB0522c, [+ 13 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1027 MSMEG1028 MSMEG1029 MSMEG1030 MSMEG1031 MSMEG1032 nrdF2 MSMEG1034
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1030_MSMEG1030_dna
CACGGACTGGTGGCTGGGCAGTAAAGAGGACAGCCCGCGCCGCATGCCCGCAGACGAGTTCGTCAACCACCTGACCACGATCATGGTCGGCTCCATCAACGGCACCTGCGAGCTGCTGGGCATCCGGATCGACCCGGATCTGCCCCTGCACGAGGGTGTGCAGCGCCGCGAACGCGCCAGTTAGTCACACCAGTCACATCGCGCAACTCTCGGGGTGGTCCGAGCGTTGACAGGTCAGCCACCGCGCCGGACACTGGCAAATATCCGGTACCGGCGTTCCCAGGAAAGGACCTGAAACCATGACGGCTGCCGACCAGCAACCCATCCGGACCCGCGCCCTGGTGATCGGCACCGGGTTCTCCGGGCTGGGCATGGCCATCGAACTGCAGCGCCGTGGCGTCGACTTCCTGATTCTGGAGAAGGCCGACGAGATCGGCGGCACCTGGCGCGACAACACCTACCCGGGATGCGCGTGCGACATCCCGTCGCACATGTACTCGTTCTCGTTCGAGCCCAAGGCCGACTGGAAGCACATGTGGTCCTTCCAGCCCGAGATCCAGGACTACCTGCTGGGCGTGACGGCCAAATACGGACTGCGCCGTCACATCCACTTCAACTCGCACGTCGACCGCGCGCACTGGGACGACGAGGAACTGCGCTGGCATGTGTTCACCAAGACCGGCCAGGAGTACATCGCCCAGTTCCTGGTGTCCGGCGCAGGCGGTCTGCACATCCCGCAGATCCCGGACATCGAAGGCCGGGAGTCGTTCGCGGGCGCGGCTTTTCACTCGGCGCAGTGGGACCACAGCGTCGATTTGCGCGGTAAGCGCGTCGCGGTGATCGGCACCGGCGCCAGTGCCATCCAGATCGTGCCGGAGATCGTCAAGGACGTCGCCGAACTGCACCTGTACCAGCGCACCCCGGCCTGGGTGATGCCACGCGTCAACAACGCGTTCCCGCAATGGCTGCGCAACGTCTTCAGCTACGTCCCCGGCACCCGCGCGCTGCTGCGCGCGGCCATCTACTGGATCCATGAGGGCGTCGGCTTCGCGATGACCAAGGAGCCGCGCCTGCTCAAGATCGGCGAGTGGATGGGCCGCTACAACATCAACCGCAGCATCAAGGACCCCGAGCTGCGGCGTAAGCTCACGCCGAGCTACCGCGCCGGGTGCAAGCGAATCCTCAACTCCGACACCTACTATCGCGGGATCGCCGACCCCAAGACCCAGGTGATCACCGAGGGCATCGCCCGGATGACGCCGACCGGCATCGTCACCAACGACGGCGTCGAGCATCCCGTCGACATCGTCGTCTACGCCACGGGCTTCCACGTGACCGACTCCTACACCTACGTCGACATCAAGGGTGCGGGCGGCGAAGACCTGGTCGACCGCTGGAACCGCGAGGGCATCCAGGCCCACCGCGGCGTCGCCGTCGCCGGCATGCCGAACCTGTTCTTCCTGCTGGGGCCGAACACCGCGCTGGGCCACAACTCGGTGGTGTTCATGATCGAGCAGCAGATTCGCTACGTCGGGCAGGCCATCGCCGCCGTCGACAAGGCGGGCGCGGCCGCGTTGGCGCCGACCCGGCGCGCGCAGGACGCGTTCAACGCCGAGTTGCAGCGGGATTTGTCCGGCACGGTGTTCAACACGGGCGGTTGCAAGAGCTGGTACCTCGACGAGCACGGCGTCAACCGGACGCTGTGGAGCGGCATGACATGGCAGTACTGGAAGGCGCTGCGCCGCCTCGATCCGTCGGAGTTCGAGTTCCTCGACCAGCGGGTTCTCGCGCGATCCTAG

Protein Sequence 

>Ms1030_MSMEG1030_protein
MTAADQQPIRTRALVIGTGFSGLGMAIELQRRGVDFLILEKADEIGGTWRDNTYPGCACDIPSHMYSFSFEPKADWKHMWSFQPEIQDYLLGVTAKYGLRRHIHFNSHVDRAHWDDEELRWHVFTKTGQEYIAQFLVSGAGGLHIPQIPDIEGRESFAGAAFHSAQWDHSVDLRGKRVAVIGTGASAIQIVPEIVKDVAELHLYQRTPAWVMPRVNNAFPQWLRNVFSYVPGTRALLRAAIYWIHEGVGFAMTKEPRLLKIGEWMGRYNINRSIKDPELRRKLTPSYRAGCKRILNSDTYYRGIADPKTQVITEGIARMTPTGIVTNDGVEHPVDIVVYATGFHVTDSYTYVDIKGAGGEDLVDRWNREGIQAHRGVAVAGMPNLFFLLGPNTALGHNSVVFMIEQQIRYVGQAIAAVDKAGAAALAPTRRAQDAFNAELQRDLSGTVFNTGGCKSWYLDEHGVNRTLWSGMTWQYWKALRRLDPSEFEFLDQRVLARS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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