MSMEG1037
ms1037
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1106170 – 1107219
Vulnerability Index (VI):
M. tuberculosis homologs adhC, adhB, adh
M. abscessus homologs MAB3400, MAB2084, MAB4560, MAB0983c, MAB4388
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1035 MSMEG1037 MSMEG1038 MSMEG1039
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1037_MSMEG1037_dna
TCAGCGTCGAGGACGCGCAGGCGCTCACCGAAGCCGATCCCTACTCGCAGGCCGGCCTGGTGAGCTACGAGCGCGTCTCGTTCAACGGTTCGATCCGCGCACCCGGTCTCTAGACGGCCGACTCGGAGCGGACTCTCAGGCCCCTGACAGGGAGCACCGTCACAGTCGATATCGGGATTACCGCGCCGTCAATCTCAGTTGCACTCTGTTGTGCCGCGCGACGTGATGCGCGCGGCGGACACCCGTGAACTGGACTAACGTCCCGGGCAGTAATGAAGAATCGACGATAAGAGGTCTGTCATGAGTACCGTTTCCGCGTATGCCGCCACCTCGGCGACCGAACCACTGACCAAGACCACCATCACCCGTCGCGCCGTGGGTCCGCACGATGTTGCGTTCGACATCCACTTCGCAGGCATCTGTCACTCCGACATCCACACCGTCAAGGCCGAGTGGGGCGTCCCGAACTACCCCGTGGTCCCCGGTCACGAGATCGCCGGCGTGGTCACCGAGGTGGGCTCGGAGGTCACCAAGTACAAGGTCGGCGACCGCGTCGGCGTCGGCTGCTTCGTCGACTCCTGCCGAGAGTGCGACAACTGCAAGGCCGGCCTGGAGCAGTACTGCACCGGCACCGGCATGGTCGGCACCTACAACGCGATCGACCGCGACGGCACCCCGACCCACGGCGGTTACAGCGGCGCCATCGTGGTCGACGAGAACTACGTGCTGCGCATCCCCGACAGCCTTCCGCTCGACGCGGCCGCTCCCCTGCTGTGTGCGGGCATCACCACCTATTCCCCGCTGCGGCACTGGAATGCCGGCCCCGGCAAGAAGGTCGCCGTCATCGGGCTCGGCGGCCTCGGCCACGTGGCCGTCAAGCTCGCCAAGGCGATGGGCGCCGATGTCACGGTGCTCAGCCAGTCGCTGAAGAAGATGGAAGACGGCCTGCGCCTGGGCGCCTCGGCCTACTACGCGACGTCCGATCCGGAGACGTTCGACAAGCTCGCCGGGTCGTTCGACCTGATCCTCAACACCGTGTCGGCGAACCTGGACCTCGGTGCCTACCTGGGCCTGCTCAAGCTCGACGGCGCGCTCGTCGAACTCGGCCTGCCCGAGCACCCCATGGAGGTCCCGGCGTTCCCGCTGCTCGCTCAGCGACGCAACCTCACCGGCTCGATGATCGGCGGCATCCCCGAGACCCAGGAGATGCTCGACTTCTGCGCCGAACACGACGTCCGGCCGGAGATCGAGATCATCACCCCCGACTACATCAACGAGGCCTACGAGCGCGTCCTGGCCAGCGATGTGCGCTACCGCTTCGTGATCGACACCGCGTCGCTGCGTAGCTGA

Protein Sequence 

>Ms1037_MSMEG1037_protein
MSTVSAYAATSATEPLTKTTITRRAVGPHDVAFDIHFAGICHSDIHTVKAEWGVPNYPVVPGHEIAGVVTEVGSEVTKYKVGDRVGVGCFVDSCRECDNCKAGLEQYCTGTGMVGTYNAIDRDGTPTHGGYSGAIVVDENYVLRIPDSLPLDAAAPLLCAGITTYSPLRHWNAGPGKKVAVIGLGGLGHVAVKLAKAMGADVTVLSQSLKKMEDGLRLGASAYYATSDPETFDKLAGSFDLILNTVSANLDLGAYLGLLKLDGALVELGLPEHPMEVPAFPLLAQRRNLTGSMIGGIPETQEMLDFCAEHDVRPEIEIITPDYINEAYERVLASDVRYRFVIDTASLRS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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