MSMEG1048
ms1048
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1116366 – 1117073
Vulnerability Index (VI):
M. tuberculosis homologs echA17, echA8, echA14, echA11, echA1, [+ 8 remaining orthologs]
M. abscessus homologs MAB3382c, MAB0903, MAB1185c, MAB0905, MAB2737c, [+ 12 remaining orthologs]
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG1043 MSMEG1044 MSMEG1045 MSMEG1046 MSMEG1047 MSMEG1048 MSMEG1049 MSMEG1050 MSMEG1051 MSMEG1052
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1048_MSMEG1048_dna
GTCGCGGCCCTCCCGGAGGGCCAGCGCGCCGACGGCGAGAACACCGAGACCGACCGGGCGTTCTGGTGCACACCGAAAGCCGGGCTCGACGACTTCGAGGCGGGGAACACCTTCCTGCTGCCGCCGACCTGGACGCAGCTGGACTCCCTCGACGGCCGCACGGTGGCCGAGGTGCTGGCGGTCGAACGCAAGATCGTGACGATCGAGCCCAGCCTGTCGACCGAGGGCAACAACTGGGAGATCGAATACTTCGACAGCGGGCGCTACAACGCTGCACGCAAGCATCGGTCGCCCGGGCAATGAACGAGTTCATCAAGATCGTCCTCGGTTCCGCGCCCGAGCAGACGGGCGTGGCCACGTTGCTGTTGTCGCGGCCCCCGACGAACGCGTTGACCCGCCAGATGTACCGCGAGATCTCCATCGCCGCGAACGAGCTCGCCCAGCGCGCCGACGTGTCGTCGGTCATCGTCTACGGCGGCCACGAGATCTTCTGCGCGGGCGACGACATCCCCGAACTGCGCACCCTCGACGCCGAAGAGACCGCGGCGGCCGACCACGCGCTGCAGCGCTGCATCGAGGCCGTTGCCGCCATCCCCAAACCCACGGTCGCGGCCGTCACCGGGTACGCGCTCGGCAGCGGGATGAACCTGGCGCTGGCCGCGGACTGGCGGGTGAGCGGCGACAACGCCAAGTTCGGCGCCACCGAGATCCTGGCGGGGCTGGCACCGCGCGGCGGCGGCGGGGTACGCCTGGCGGACGCCATCGGGACCAGCAAGGCCAAGGAGCTCGTGTTCAGCGGCCGGTTCGTCGGCGCCGAGGAAGCGCTCGAGATCGGCCTGGTCGACGAGATGGTGGCACCCGACCACGTCTACGAGGCCGCGCTCGCGTGGGCCCGCCGGTTCTCCGACCATCCGGTCGACGTGCTGGCCGCCGCGAAAGCCTCCCTCAACGGGCCGGTCAACTGGCGGGGCCCCCGCCCGACCGATCGGATGGTGGACCGGCCCTGA

Protein Sequence 

>Ms1048_MSMEG1048_protein
MNEFIKIVLGSAPEQTGVATLLLSRPPTNALTRQMYREISIAANELAQRADVSSVIVYGGHEIFCAGDDIPELRTLDAEETAAADHALQRCIEAVAAIPKPTVAAVTGYALGSGMNLALAADWRVSGDNAKFGATEILAGLAPRGGGGVRLADAIGTSKAKELVFSGRFVGAEEALEIGLVDEMVAPDHVYEAALAWARRFSDHPVDVLAAAKASLNGPVNWRGPRPTDRMVDRP

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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