MSMEG2305
ms2305
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2387651 – 2388226
Vulnerability Index (VI):
M. tuberculosis homologs Rv0067c, Rv3055, Rv3830c, Rv3557c
M. abscessus homologs MAB0085c, MAB4046c, MAB1873c, MAB1525c, MAB0579c, [+ 1 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2301 MSMEG2302 MSMEG2303 MSMEG2304 MSMEG2305 MSMEG2306 MSMEG2307 MSMEG2308 MSMEG2309
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2305_MSMEG2305_dna
CCCCTCGAGCACAGGTCCGGTGACGTCTCCCGCGATCGGGATCAGGTGGTCGAACAGCCAGGCGTGCGCGATCTCGGGGATCTCGTCGGCCTCCGTCCAGACGCGCAACAGATCCGCGTAATCGACCTGATGGGGAGGCGTGAAGATGCCGAACTGCACATTCTCGGCAAGTGACATGGGCGGGCCTTTCACCGGATGCCGACGGACGGGCGCACCCGCCTGGCACCATATAAGCGGAACAATGCTCCCCCTACGATACGGAGCGTCGTTCCGCTTATCAAGGGACGAGAGGATCTCCGGATGCCCGACGCCGACAAGACGACGCGAAAGCGCGCCGACGCGCGCCGCAACGAGCAGGCGCTTCTGGAGGCCGCGGCCGCGGCGTTCGTGGCCGCGGGCGTGGAGGTGCCGGTGCGCGATATCGCGGCCCGCGCCGGCGTCGGCATGGGCACCATCTACCGGCACTTCCCCACGCGCGCCGACCTGATCATCGCGGTGTACCGCCACCAGGTCGACGCGTGCGCCGACGCCGGGCCGCAACTGTTGGAACAGACCACGCCGTACGCCGCGCTGGCGAAGTGGGTCGACCAGTTCGTGGACTTCCTGGTGACCAAGCACGGCCTGGCCGCGGCGCTGCATTCGGACAACGCCCGGTACCAGACCCTGCACACCTACTTCCTCGACCGGCTGCTCCCGGTGTGCGCACAGCTCCTGGATGCCGCCGTCGCCTCAAATGAAATCTGTTCGGGCGTCGACCCGTACGTCTTCATGCGTGCGATCGGCAACCTCTGCATCGGCGCCGAAGACGATCCCCGTTACGACGCCCGCGCGATGGTGGCGGTGCTGATCAACGGGCTGCGTCGGCCATCGGAGTGA

Protein Sequence 

>Ms2305_MSMEG2305_protein
MPDADKTTRKRADARRNEQALLEAAAAAFVAAGVEVPVRDIAARAGVGMGTIYRHFPTRADLIIAVYRHQVDACADAGPQLLEQTTPYAALAKWVDQFVDFLVTKHGLAAALHSDNARYQTLHTYFLDRLLPVCAQLLDAAVASNEICSGVDPYVFMRAIGNLCIGAEDDPRYDARAMVAVLINGLRRPSE

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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