MSMEG2307
ms2307
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2388350 – 2389228
Vulnerability Index (VI):
M. tuberculosis homologs Rv0791c, Rv1855c, Rv2893, Rv0044c, Rv2951c
M. abscessus homologs MAB4496c, MAB4797, MAB0968c, MAB3792, MAB3016c, [+ 7 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2302 MSMEG2303 MSMEG2304 MSMEG2305 MSMEG2306 MSMEG2307 MSMEG2308 MSMEG2309 MSMEG2310
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2307_MSMEG2307_dna
CGCGTGGGGAAGTGCCGGTAGATGGTGCCCATGCCGACGCCGGCGCGGGCCGCGATATCGCGCACCGGCACCTCCACGCCCGCGGCCACGAACGCCGCGGCCGCGGCCTCCAGAAGCGCCTGCTCGTTGCGGCGCGCGTCGGCGCGCTTTCGCGTCGTCTTGTCGGCGTCGGGCATCCGGAGATCCTCTCGTCCCTTGATAAGCGGAACGACGCTCCGTATCGTAGGGGGAGCATTGTTCCGCTTATATGGTGCCAGGCGGGTGCGCCCGTCCGTCGGCATCCGGTGAAAGGCCCGCCCATGTCACTTGCCGAGAATGTGCAGTTCGGCATCTTCACGCCTCCCCATCAGGTCGATTACGCGGATCTGTTGCGCGTCTGGACGGAGGCCGACGAGATCCCCGAGATCGCGCACGCCTGGCTGTTCGACCACCTGATCCCGATCGCGGGAGACGTCACCGGACCTGTGCTCGAGGGGTGGACGCTACTGTCGGCGCTCGCGGCGCAGACGAAGCGTCTGCGTATCGGTTTGATGGTGACCAGCAACAGGTTTCGGCCACCGTCCATGCTCGCCAAGATCGCCACGACCGTCGACATCGTGTCCGGTGGTCGTCTCGATTTCGGCATCGGGTCGGGCTCGCGGCCCGGTCATCCCGTCGCACGGCACGAGTACATCTCGAACGGGCTGCCCTACCACGACGCCGACCACGCGGTCGCGAGTCTGGCCGAGGCGTGCACGCTGATCCGCCGGTTGTGGGCCGAGGAGGAACCGTTTGACTTCGACGGCGGCTTCTACCGATTGGAGCGCGCGTTCGCCAACCCCAAACCGGTGCAGCGGCCCCACCCGCCGATCGTCATCGGCGGACGCGCCAAGGCCACGCTCCGAGTGGTTGCCGAACACGCCGACGTCTGGAACATCCCCGGCGGCGACATCGAGGACATGGTGCGCCGCAGCGAGATGCTCGACAGTTACTGCGCCGAAATCGGCCGGGACCCAAAGGAGATCGCGCGGTCCACGGTGCTCGGAGTGTCCTACGACCAGCCGGGGCAGACCCGGGCCGCGGTGAAAGAAGCCGTCGACGCCGGGTTCGGCCACATCGTCCTGATGCTGCCGACCCCGTACCCCGACAACGTCGTCCGCTGGGGCGTCGACGAAATCGTCACGCCCACGGCGTCATAG

Protein Sequence 

>Ms2307_MSMEG2307_protein
MSLAENVQFGIFTPPHQVDYADLLRVWTEADEIPEIAHAWLFDHLIPIAGDVTGPVLEGWTLLSALAAQTKRLRIGLMVTSNRFRPPSMLAKIATTVDIVSGGRLDFGIGSGSRPGHPVARHEYISNGLPYHDADHAVASLAEACTLIRRLWAEEEPFDFDGGFYRLERAFANPKPVQRPHPPIVIGGRAKATLRVVAEHADVWNIPGGDIEDMVRRSEMLDSYCAEIGRDPKEIARSTVLGVSYDQPGQTRAAVKEAVDAGFGHIVLMLPTPYPDNVVRWGVDEIVTPTAS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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