serB
ms1041
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1110747 – 1111988
Vulnerability Index (VI):
M. tuberculosis homologs serB2, Rv3661
M. abscessus homologs MAB3388c, MAB0431c
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG1039 ctaD serB MSMEG1042 MSMEG1043 MSMEG1044 MSMEG1045 MSMEG1046
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1041_serB_dna
TGTGGAACGTGTTCAAGAGCTGGCGTTACGGCGAGCCCGTCACGGTCGACGATCCGTGGGGCTACGGCAACTCCCTGGAGTGGGCCACCAGCTGCCCGCCGCCGCGGCACAACTTCACCGAGCTGCCGCGTATCCGGTCGGAGCGTCCGGCGTTCGAGCTGCACTACCCGCACATGGTCGAGCGGATGCGGGCCGAGGCCCACGTGGGTCGCGCCCACCATCCCGAGCTCGAGACCGCGGACAAGTCCAGCTGACGCCTTCGCGCCAACTGGGTGAACAACTGAGAAGGTGACCTGTAGATGAGCTCGGCACGCGAGCGCTCATCGCTACTGATCACCGTCACCGGTGTCGACCAGCCGGGCGTCACCTCGGCACTGTTCGAGGTGCTGTCCCGGCACAAGGTCGAGCTGCGCAACGTCGAGCAGGTCGTGATCCGCGGCCGGCTCACGTTGGGCGTTCTGGTGGCCGCGCCGTCCGACGTGGCCGACGGCGATGATCTGCGACGCGACGTCGAGGCCGCCATCCACGGCGTGGGTCTCGACGTCGCGATCGAACGCAGCGACGACCTGCCGGTGATGCGTGAGCCCTCAACCCACACGATCGTGGTGCTGGGCCGTCCGATCACCGCCGAGGCGTTCGGGGTGGTCGCCCGCGCGGTGGCCGATCTGGGCGTCAACATCGATTTCATCCGCGGCGTCTCCGACTACCCGGTGACGGGGCTGGAGCTGCGCGTGTCGGTCCCGGCGGGCGCGGCCTACGGGCAGTTGCAGCAGGCGCTCGCCACGGTCGCCGCGAACGAGGGCGTCGACATCGCGCTGGAGGACTACACGCTGTCACGACGGGCCAAGCGGCTCATCGTGTTCGACGTCGACTCGACCCTCATCCAGGGTGAGGTGATCGAGATGCTGGCCGAGCACGCCGGTGCCGCGGCAGCCGTCGCCGAGGTGACCGAGGCCGCGATGCGGGGTGAACTCGACTTCGCCGAGTCTTTGCACCGCCGGGTCGCGACGCTCGCCGGGCTGCCTGCCTCGGTACTCGACGAGGTCGCCGAGCAGTTGGAGCTCACACCGGGGGCGCGGACCACGATCCGCACCCTCCGCAGGCTGGGCTACTACTGCGGTGTGGTCTCGGGCGGATTCCGCCAGGTCATCGAACCGCTCGCGCACGAACTCATGCTCGACTACGTCGCGGCCAACGAACTGGAGATCGTCGACGGCAAGCTCACCGGACGCGTCGTCGGCGACGTCGTGGACCGGCCGGGCAAGGCCAAGGCGCTGCGGGACTTCGCCCAGCAGGTCGGCGTACCGATGGAGCAGACCGTCGCCGTCGGCGACGGCGCCAACGACATCGACATGCTGTCGGCCGCGGGCCTCGGGGTGGCGTTCAACGCCAAACCCGCGCTGCGTGAGGTGGCCGACGCGTCACTGAGCCATCCGTACCTGGACACCGTGCTGTTCATCCTGGGCATCACGCGCGGCGAGATCGAGGCCGCCGATGCGCTCGACGGTGTGGTGCGCCGCGTCGAGATCCCGGATTATTAG

Protein Sequence 

>Ms1041_SerB_protein
MSSARERSSLLITVTGVDQPGVTSALFEVLSRHKVELRNVEQVVIRGRLTLGVLVAAPSDVADGDDLRRDVEAAIHGVGLDVAIERSDDLPVMREPSTHTIVVLGRPITAEAFGVVARAVADLGVNIDFIRGVSDYPVTGLELRVSVPAGAAYGQLQQALATVAANEGVDIALEDYTLSRRAKRLIVFDVDSTLIQGEVIEMLAEHAGAAAAVAEVTEAAMRGELDFAESLHRRVATLAGLPASVLDEVAEQLELTPGARTTIRTLRRLGYYCGVVSGGFRQVIEPLAHELMLDYVAANELEIVDGKLTGRVVGDVVDRPGKAKALRDFAQQVGVPMEQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLSHPYLDTVLFILGITRGEIEAADALDGVVRRVEIPDY

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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