MSMEG1046 (MSMEG1046)

background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 serB MSMEG1042 MSMEG1043 MSMEG1044 MSMEG1045 MSMEG1046 MSMEG1047 MSMEG1048 MSMEG1049 MSMEG1050
Species: M. smegmatis
Strain: MC2-155
PATRIC Annotation: -
Synonyms:
M. tuberculosis homologs RVBD3041c, RVBD1687c, RVBD1747, proV, RVBD1458c, [+ 6 remaining orthologs]
M. abscessus homologs MAB3384c, MAB2461, MAB1502, MAB3698, MAB1655, [+ 14 remaining orthologs]
Gene Start: 1114707
Gene End: 1115555
Vulnerability Index (VI):
VI Lower Bound:
VI Upper Bound:
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB]

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [Akusobi et al. (2022)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]


DNA and Protein Sequence help

DNA Sequence

ACCGTGCTCTACATCGGCGCCGGTCTCGGTCCCGGGCCGCGCGACGGCCTGATGACCGGCCTCGTGGCGCGTACCGGGCTGTCGGTGCGACTCGTCCGCACGTGCATCGAGGCCACCGTGCTGGCCGTCGGATGGCTCATGGGCGGGACCGTCGGTGTGGGAACGGTCCTGTACGCCTTCGGGATCGGCCCGCTGGTGCAGTTGTTCCTCAGACTCACCCCGCGCCGCATCCTGTTCCACGATTTCGGCGCGCCCGGGCGTAACCGGGCGAGCGGCGAGGACATCACTACGATGAGCGGGTGCCCACAACCGGAGAAGACGCAGCCGACAACCCAGACCTGCTGATCGACTTCGCCAGGGTCACCCTGAGGCGCGGGGGCAACACCCTCGTCGGGCCCATCACCTGGGCTGTCGAACTCGACGAGCGCTGGGTCGTCATCGGTCCCAACGGCGCAGGCAAGACCTCGCTGTTGCGCATCGCCGCGGCGACCGAACACCCGTCGTCGGGAACCGCCTACGTACTGGGGGAGCGGCTGGGCCGCACCGACATGGCCGAACTGCGTTCGCGCGTCGGCCTGAGCAGCTCGGCTCTGTCGCAACGGATTCCCGACGACGAGATCGTCCGCGACCTCGTCGTGTCGGCCGGGTACGCGGTGCTCGGGCGGTGGCGCGAGCAGTACGACGACGTCGACTACGAGCAGGCCGTGAACATGCTCGAAAGCGTCGGCGCCGAGCACCTCGCCGAACGCCGGTACGGCACCCTGTCGGAGGGCGAACGCAAACGCGTCCTGATCGCCCGGTCGCTCATGACCGACCCGGAACTCCTGCTGCTCGACGAGCCCGCGGCCGGGCTCGACCTCGGCGGCCGCGAGGACCTCGTGGCCCGTCTCACCGACCTCGCCGCCGACCCCGATGCACCGGCCATGGTGCTCGTGACGCACCATGTCGAGGAGATCCCGGTCGGGTTCAGCCACGGCTTGATCCTGTCCGAGGGCAAGGTGGTGGCCTCCGGTCTGCTCACCGATGTGCTGACGTCCGAGAACCTGTCCAAGGCATTCGGCCAGGCCATCGCCCTCGAGGTGATCGACGGACGGTACTTCGCGCGCCGGGTGAGGAGCCGGGCAGCGCACAGGAGGCGAAATGACTGA

Protein Sequence

VPTTGEDAADNPDLLIDFARVTLRRGGNTLVGPITWAVELDERWVVIGPNGAGKTSLLRIAAATEHPSSGTAYVLGERLGRTDMAELRSRVGLSSSALSQRIPDDEIVRDLVVSAGYAVLGRWREQYDDVDYEQAVNMLESVGAEHLAERRYGTLSEGERKRVLIARSLMTDPELLLLDEPAAGLDLGGREDLVARLTDLAADPDAPAMVLVTHHVEEIPVGFSHGLILSEGKVVASGLLTDVLTSENLSKAFGQAIALEVIDGRYFARRVRSRAAHRRRND_ 
Gene not present in the RLC0011 CRISPRi library.

Specific References

General References